University of Washington
Nanopore Physics Lab
Left to right: Andrew Laszlo, Henry Brinkerhoff, Dr. Brian Ross, Jon Craig, Jenny Mae Samson, Matt Noakes, Kenji Doering, Kyle Langford, Ian Nova, Dr. Jens Gundlach, Dr. Ian Derrington
Our most recent major publication is: Decoding long nanopore sequencing reads of natural DNA in the journal Nature Biotechnology. This paper demonstrated long nanopore reads of DNA that could then be used for species identification, genome scaffolding, and SNP detection. Another recent publication is: Detection and mapping of 5-methylcytosine and
5-hydroxymethylcytosine with nanopore MspA in the journal PNAS. This paper showed single molecule detection of methylcytosine on DNA using the MspA nanopore.
Mutual Information between Discrete and Continuous Data Sets
Detection and mapping of 5-methylcytosine and
5-hydroxymethylcytosine with nanopore MspA
Molecular Dynamics Study of MspA Arginine-Mutants Predicts Slow DNA Translocations and Ion Current
Blockades Indicative of DNA Sequence.
Reading DNA at single-nucleotide resolution with a mutant MspA nanopore and phi29 DNA polymerase
|Address: B033 Physics-Astronomy Building University of Washington 3910 15th Ave. NE Seattle, WA 98195-1560
Update: March 4, 2013